iupac

Joint Session Symposium

CHEM-BIO-TECH2007

IUPAC is launching through its Division of Organic & Biomolecular Chemistry a combined Biomolecular-Biotechnology Symposium as a major component of the 41st IUPAC Congress. This four-day CHEM-BIO-TECH Symposium comprises IUPAC’s 1st Symposium on Chemical Biotechnology (ISCB-1) held jointly with IUPAC’s 8th ISBOC meeting. In designing the program, the goal has been to focus on work at the interface of biotechnology and biomolecular chemistry from which many key industrial and academic advances have sprung. The program embraces a variety of topics ranging from novel drug discovery, biosynthesis, biocatalysis and organic synthesis through artificial enzymes and other emerging biotechnological applications. Attention will be devoted to the industry’s experience in drug research and in biotechnological production. We have invited speakers whom we believe will deliver exciting science.

Chair
Prof Francesco Nicotra, University of Milano Bicocca, Italy
francesco.nicotra@unimib.it

Co-Chair
Prof. Mary Garson, University of Queensland, U.S.A.
m.garson@uq.edu.au

Session Topics:

Natural products, synthesis, biosynthesis, isolation
Chair: : Prof Mary Garson
Keynotes:
- Ian Paterson, University of Cambridge, UK
  “Synthesis of marine natural products as promising anticancer agents”
- Gabriele König, University of Bonn, Germany
  “Strategies for the discovery of structurally novel natural products”
- Barbara Potts, Nereus Pharmaceuticals, USA
  “NPI-0052 (Salinosporamide A): Chemical Challenges with Practical Solutions”
Industrial application of bio-organic chemistry and biotechnology
Chair: Prof. Francesco Nicotra
Keynotes:
- Chris Guske, Tate&Lyle, USA
  “Metabolic Engineering for Profit - Know the Endgame”
- Frank Petersen, Novartis, Switzerland
  “Natural Product - Roles in cultural Development and Relevance for Medical Research”
- Pierfausto Senesi, University of Milan, Italy
  “Novel concepts in the design of kinase inhibitors as treatments for CNS diseases”
- Klaus Müller, Roche, Switzerland
  “Molecular design beyond potency and selectivity”
Bio-organic and bio-inorganic chemistry, biosynthesis, biocatalysis, artificial enzymes (1)
Chair: Prof Krishna Ganesh
Keynotes:
- Craig Townsend, JohnsHopkins University, USA
  “Dissection of iterative type I PKS function”
- Christopher Schofield, University of Oxford, UK
  “The Molecular Mechanism of the Hypoxic Response”
- Rüdolf Allemann, University of Cardiff, UK
  “Chemical wizardry: the generation of structural diversity in terpene biosynthesis”
- Liangren Zhang, University of Beijing, China
  “Calcium signal pathway targeted nucleotide: design and synthesis of cyclic ADP-ribose”
Natural products, nucleic acids
Chair: Prof Lihe Zhang
Keynotes:
- Atta-ur-Rahman, University of Karachi, Pakistan
  “Bioactive substances of natural origin – recent advances”
- Serge Beaucage, FDA, USA
  “Progress in the synthesis of thermolytic DNA oligonucleotide prodrugs and oligoribonucleotides for potential therapeutic applications”
- Michael Blackburn, University of Sheffield, UK
  “Understanding and mis-understanding transition states for enzyme reactions - the case for phosphate esters”
Analytical methods applied to molecular recognition, proteomics and metabolomics
Chair: Prof. Jonathan M. Blackburn
Keynotes:
- Jesus Jimenez Barbero, CSIC, Spain
  “Biomolecular interactions: The specific recognition of carbohydrates by proteins. A 3D view using NMR”
- Gary Siuzdak, Scripps Centre for Mass Spectrometry, USA
  “Exploring the Limits of Mass Spectrometry in Biochemical Research”
Bio-organic and bio-inorganic chemistry, biosynthesis, biocatalysis, artificial enzymes (2)
Chair: Prof Vadim Ivanov
Keynotes:
- James Cowan, Ohio State University, USA
  “Catalytic metalloDrugs - A new paradigm for drug design”
- Stefan Matile, University of Geneva, Switzerland
  “Artificial Tongues and Leaves”
- Alexandre Gabibov, Russian Academy of Sciences, Russia
  “Artificial enzymes and abzymes”


Joint Session Symposium CHEM-BIO-TECH2007 IUPAC is launching through its Division of Organic & Biomolecular Chemistry a combined Biomolecular-Biotechnology Symposium as a major component of the 41st IUPAC Congress. This four-day CHEM-BIO-TECH Symposium comprises IUPAC’s 1st Symposium on Chemical Biotechnology (ISCB-1) held jointly with IUPAC’s 8th ISBOC meeting. In designing the program, the goal has been to focus on work at the interface of biotechnology and biomolecular chemistry from which many key industrial and academic advances have sprung. The program embraces a variety of topics ranging from novel drug discovery, biosynthesis, biocatalysis and organic synthesis through artificial enzymes and other emerging biotechnological applications. Attention will be devoted to the industry’s experience in drug research and in biotechnological production. We have invited speakers whom we believe will deliver exciting science. Chair Prof Francesco Nicotra, University of Milano Bicocca, Italy francesco.nicotra@unimib.it Co-Chair Prof. Mary Garson, University of Queensland, U.S.A. m.garson@uq.edu.au Session Topics: Natural products, synthesis, biosynthesis, isolation Chair: : Prof Mary Garson Keynotes: Ian Paterson, University of Cambridge, UK “Synthesis of marine natural products as promising anticancer agents” Gabriele König, University of Bonn, Germany “Strategies for the discovery of structurally novel natural products” Barbara Potts, Nereus Pharmaceuticals, USA “NPI-0052 (Salinosporamide A): Chemical Challenges with Practical Solutions” Industrial application of bio-organic chemistry and biotechnology Chair: Prof. Francesco Nicotra Keynotes: Chris Guske, Tate&Lyle, USA “Metabolic Engineering for Profit - Know the Endgame” Frank Petersen, Novartis, Switzerland “Natural Product - Roles in cultural Development and Relevance for Medical Research” Pierfausto Senesi, University of Milan, Italy “Novel concepts in the design of kinase inhibitors as treatments for CNS diseases” Klaus Müller, Roche, Switzerland “Molecular design beyond potency and selectivity” Bio-organic and bio-inorganic chemistry, biosynthesis, biocatalysis, artificial enzymes (1) Chair: Prof Krishna Ganesh Keynotes: Craig Townsend, JohnsHopkins University, USA “Dissection of iterative type I PKS function” Christopher Schofield, University of Oxford, UK “The Molecular Mechanism of the Hypoxic Response” Rüdolf Allemann, University of Cardiff, UK “Chemical wizardry: the generation of structural diversity in terpene biosynthesis” Liangren Zhang, University of Beijing, China “Calcium signal pathway targeted nucleotide: design and synthesis of cyclic ADP-ribose” Natural products, nucleic acids Chair: Prof Lihe Zhang Keynotes: Atta-ur-Rahman, University of Karachi, Pakistan “Bioactive substances of natural origin – recent advances” Serge Beaucage, FDA, USA “Progress in the synthesis of thermolytic DNA oligonucleotide prodrugs and oligoribonucleotides for potential therapeutic applications” Michael Blackburn, University of Sheffield, UK “Understanding and mis-understanding transition states for enzyme reactions - the case for phosphate esters” Analytical methods applied to molecular recognition, proteomics and metabolomics Chair: Prof. Jonathan M. Blackburn Keynotes: Jesus Jimenez Barbero, CSIC, Spain “Biomolecular interactions: The specific recognition of carbohydrates by proteins. A 3D view using NMR” Gary Siuzdak, Scripps Centre for Mass Spectrometry, USA “Exploring the Limits of Mass Spectrometry in Biochemical Research” Bio-organic and bio-inorganic chemistry, biosynthesis, biocatalysis, artificial enzymes (2) Chair: Prof Vadim Ivanov Keynotes: James Cowan, Ohio State University, USA “Catalytic metalloDrugs - A new paradigm for drug design” Stefan Matile, University of Geneva, Switzerland “Artificial Tongues and Leaves” Alexandre Gabibov, Russian Academy of Sciences, Russia “Artificial enzymes and abzymes”